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Dicyemid Mesozoans: A Unique Parasitic Lifestyle and a Reduced Genome
https://oist.repo.nii.ac.jp/records/1124
https://oist.repo.nii.ac.jp/records/1124974b11dd-ddae-4d63-9974-fed310200e43
名前 / ファイル | ライセンス | アクション |
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Lu-2019-Dicyemid Mesozoans_ A Unique Parasitic (722.3 kB)
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Creative Commons Attribution 4.0 International (https://creativecommons.org/licenses/by/4.0/)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-10-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Dicyemid Mesozoans: A Unique Parasitic Lifestyle and a Reduced Genome | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Lu, Tsai-Ming
× Lu, Tsai-Ming× Kanda, Miyuki× Furuya, Hidetaka× Satoh, Noriyuki |
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書誌情報 |
en : Genome Biology and Evolution 巻 11, 号 8, p. 2232-2243, 発行日 2019-07-26 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Dicyemids, previously called "mesozoans" (intermediates between unicellular protozoans and multicellular metazoans), are an enigmatic animal group. They have a highly simplified adult body, comprising only approximately 30 cells, and they have a unique parasitic lifestyle. Recently, dicyemids were shown to be spiralians, with affinities to the Platyhelminthes. In order to understand molecular mechanisms involved in evolution of this odd animal, we sequenced the genome of Dicyema japonicum and a reference transcriptome assembly using mixed-stage samples. The D. japonicum genome features a high proportion of repetitive sequences that account for 49% of the genome. The dicyemid genome is reduced to approximately 67.5 Mb with 5,012 protein-coding genes. Only four Hox genes exist in the genome, with no clustering. Gene distribution in KEGG pathways shows that D. japonicum has fewer genes in most pathways. Instead of eliminating entire critical metabolic pathways, parasitic lineages likely simplify pathways by eliminating pathway-specific genes, while genes with fundamental functions may be retained in multiple pathways. In principle, parasites can stand to lose genes that are unnecessary, in order to conserve energy. However, whether retained genes in incomplete pathways serve intermediate functions and how parasites overcome the physiological needs served by lost genes, remain to be investigated in future studies. | |||||
出版者 | ||||||
出版者 | Oxford University Press on behalf of the Society for Molecular Biology and Evolution | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1759-6653 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/31347665 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1093/gbe/evz157 | |||||
権利 | ||||||
権利情報 | © 2019 The Author(s). | |||||
情報源 | ||||||
関連名称 | https://creativecommons.org/licenses/by/4.0/ | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://academic.oup.com/gbe/article/11/8/2232/5536717?searchresult=1 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |