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アイテム
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(2018), Colorectal carcinoma: Ex vivo evaluation using q‐space imaging; Correlation with histopathologic findings. J. Magn. Reson. Imaging, 48: 1059-1068. doi:10.1002/jmri.26018, which has been published in final form at https://doi.org/10.1002/jmri.26018. 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Colorectal carcinoma: Ex vivo evaluation using q-space imaging; Correlation with histopathologic findings
https://oist.repo.nii.ac.jp/records/732
https://oist.repo.nii.ac.jp/records/7326d372a7d-a927-4d30-b756-7bf4af321a54
名前 / ファイル | ライセンス | アクション |
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Yamada_JMRI_2018_Accepted Version (1.5 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-03-31 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Colorectal carcinoma: Ex vivo evaluation using q-space imaging; Correlation with histopathologic findings | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Yamada, Ichiro
× Yamada, Ichiro× Hikishima, Keigo× Yoshino, Norio× Sakamoto, Junichiro× Miyasaka, Naoyuki× Yamauchi, Shinichi× Uetake, Hiroyuki× Yasuno, Masamichi× Saida, Yukihisa× Tateishi, Ukihide× Kobayashi, Daisuke× Eishi, Yoshinobu |
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書誌情報 |
en : Journal of Magnetic Resonance Imaging 巻 48, 号 4, p. 1059-1068, 発行日 2018-03-30 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | BACKGROUND: Although the prognosis of colorectal carcinoma (CRC) patients depends on the histologic grade (HG) and lymph node metastasis (LNM), accurate preoperative assessment of these prognostic factors is often difficult. PURPOSE: To assess the HG and extent of LNM by q-space imaging (QSI) for preoperative diagnosis of CRC. STUDY TYPE: Prospective. SPECIMEN: A total of 20 colorectal tissue samples containing adenocarcinomas and resected lymph nodes (LNs). FIELD STRENGTH/SEQUENCE: QSI was performed with a 3T MRI system using a diffusion-weighted echo-planar imaging sequence: repetition time, 10,000 msec; echo time, 216 or 210 msec; field of view, 113 x 73.45 mm; matrix, 120 x 78; section thickness, 4 mm; and 11 b values ranging from 0 to 9000 s/mm(2) . ASSESSMENT: The mean displacement (MDP; mum), zero-displacement probability (ZDP; arbitrary unit [a.u.]), kurtosis (K; a.u.), and apparent diffusion coefficient (ADC) were analyzed by two observers and compared with histopathologic findings. STATISTICAL TESTS: Spearman's rank correlation coefficient, Mann-Whitney U-test, and ROC curve analyses. RESULTS: For all 20 carcinomas, the MDP, ZDP, K, and ADC were 8.87 +/- 0.37 mum, 82.0 +/- 6.2 a.u., 74.3 +/- 3.0 a.u., and 0.219 +/- 0.040 x 10(-3) mm(2) /s, respectively. The MDP (r = -0.768; P < 0.001), ZDP (r = 0.768; P < 0.001), and K (r = 0.785; P < 0.001) were significantly correlated with the HG of CRC, but not the ADC (r = 0.088; P = 0.712). There were also significant differences in the MDP, ZDP, and K between metastatic and nonmetastatic LNs (all, P < 0.001), but not the ADC (P = 0.082). In the HG of CRC and LNM, the area under the curve was significantly greater for MDP, ZDP, and K than for ADC. DATA CONCLUSION: QSI provides useful diagnostic information to assess the HG and extent of LNM in CRC. LEVEL OF EVIDENCE: 1 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;48:1059-1068. |
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出版者 | ||||||
出版者 | John Wiley & Sons, Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1522-2586 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1053-1807 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/29601149 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1002/jmri.26018 | |||||
権利 | ||||||
権利情報 | © 2018 International Society for Magnetic Resonance in Medicine | |||||
権利 | ||||||
権利情報 | This is the peer reviewed version of the following article: Yamada, I. , Hikishima, K. , Yoshino, N. , Sakamoto, J. , Miyasaka, N. , Yamauchi, S. , Uetake, H. , Yasuno, M. , Saida, Y. , Tateishi, U. , Kobayashi, D. and Eishi, Y. (2018), Colorectal carcinoma: Ex vivo evaluation using q‐space imaging; Correlation with histopathologic findings. J. Magn. Reson. Imaging, 48: 1059-1068. doi:10.1002/jmri.26018, which has been published in final form at https://doi.org/10.1002/jmri.26018. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://onlinelibrary.wiley.com/doi/full/10.1002/jmri.26018 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |