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Oral carcinoma: Clinical evaluation using diffusion kurtosis imaging and its correlation with histopathologic findings
https://oist.repo.nii.ac.jp/records/733
https://oist.repo.nii.ac.jp/records/733b9cb8e41-73fd-4e2e-ab56-cc262f3a587b
名前 / ファイル | ライセンス | アクション |
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Yamada_MRI_2018_Accepted Version (1.9 MB)
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Creative Commons
Attribution-NonCommercial-NoDerivatives 4.0 International (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-04-16 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Oral carcinoma: Clinical evaluation using diffusion kurtosis imaging and its correlation with histopathologic findings | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Yamada, Ichiro
× Yamada, Ichiro× Yoshino, Norio× Hikishima, Keigo× Sakamoto, Junichiro× Yokokawa, Misaki× Oikawa, Yu× Harada, Hiroyuki× Kurabayashi, Tohru× Saida, Yukihisa× Tateishi, Ukihide× Yukimori, Akane× Izumo, Toshiyuki× Asahina, Shun |
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書誌情報 |
en : Magnetic Resonance Imaging 巻 51, p. 69-78, 発行日 2018-04-26 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | PURPOSE: In this study, we aimed to determine the usefulness of diffusion kurtosis imaging (DKI) as a noninvasive method for evaluation of the histologic grade and lymph node metastasis in patients with oral carcinoma. MATERIALS AND METHODS: Twenty-seven patients with oral carcinoma were examined with a 3-T MR system and 16-channel coil. DKI data were obtained by a single-shot echo-planar imaging sequence with repetition time, 10,000ms; echo time, 94ms; field of view, 250x204.25ms; matrix, 120x98; section thickness, 4mm; four b values of 0, 500, 1000, and 2000s/mm(2); and motion-probing gradients in three orthogonal directions. Diffusivity (D) and kurtosis (K) were calculated using the equation: S=S0 exp(-b D+b(2) D(2) K/6). Conventional apparent diffusion coefficient (ADC) was also calculated. The MR images were compared with the histopathologic findings. RESULTS: Relative to the histologic grades (Grades 1, 2, and 3) of the 27 oral carcinomas, D values showed a significant inverse correlation (r=-0.885; P<0.001) and K values showed a significant positive correlation (r=0.869; P<0.001), whereas ADC values showed no significant correlation (r=-0.311; P=0.115). When comparing between metastatic and non-metastatic lymph nodes, significant differences in the D values (P<0.001) and K values (P<0.001), but not the ADC values (P=0.110) became apparent. CONCLUSIONS: In patients with oral carcinoma, DKI seems to be clinically useful for the evaluation of histologic grades and lymph node metastasis. |
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出版者 | ||||||
出版者 | Elsevier Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0730-725X | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1873-5894 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/29704561 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1016/j.mri.2018.04.014 | |||||
権利 | ||||||
権利情報 | © 2018 Elsevier Inc. | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.sciencedirect.com/science/article/pii/S0730725X1830081X?via%3Dihub#bi0005 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |