WEKO3
アイテム
{"_buckets": {"deposit": "223a96c9-965d-42f8-8901-149df9b46faa"}, "_deposit": {"created_by": 22, "id": "764", "owners": [22], "pid": {"revision_id": 0, "type": "depid", "value": "764"}, "status": "published"}, "_oai": {"id": "oai:oist.repo.nii.ac.jp:00000764", "sets": ["84"]}, "author_link": [], "item_10006_creator_3": {"attribute_name": "Author", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Lee, Ray Xin", "creatorNameLang": "en"}]}]}, "item_10006_date_granted_11": {"attribute_name": "Degree Conferral Date", "attribute_value_mlt": [{"subitem_dategranted": "2018-11-30"}]}, "item_10006_degree_grantor_9": {"attribute_name": "Degree Conferrral Institution", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_name": "Okinawa Institute of Science and Technology Graduate University "}], "subitem_degreegrantor_identifier": [{"subitem_degreegrantor_identifier_name": "38005", "subitem_degreegrantor_identifier_scheme": "kakenhi"}]}]}, "item_10006_degree_name_8": {"attribute_name": "Degree", "attribute_value_mlt": [{"subitem_degreename": "Doctor of Philosophy "}]}, "item_10006_description_7": {"attribute_name": "Abstract", "attribute_value_mlt": [{"subitem_description": "Awake animals switch between different behavioral states irregularly even in a homogenous and steady environment, especially obvious outside from any behavioral task when they are free to voluntarily behave. These irregular but structured patterns have been taken as a representation of internal states such as emotion, and are believed to represent underlying background brain activity and its dynamics. To date, the nature and source of animal spontaneous behaviors remain as a major conceptual challenge to academia, due to the lack of approaches to systematically and quantitatively examine this fundamental process. To achieve insights about the neural substrate of animal spontaneous behaviors, the research was conducted in two directions: (i) To interpret previously challenging and inconclusive behavioral development by re-evaluating spontaneous behaviors that represent emotionality, centered on the study of PTSD (post-traumatic stress disorder)-like internal psychological development in laboratory mice; (ii) To demonstrate a driving and control principle explaining fine-scale and global observations of neuronal and behavioral dynamics in spontaneously behaving mice, by two-photon calcium imaging of neuronal populations across cerebral cortical layers and areas. The results from these investigations provide the first system-level view of experimentally disentangled components, processes, and determinants explaining the nature and source of animal spontaneous behaviors.", "subitem_description_type": "Other"}]}, "item_10006_dissertation_number_12": {"attribute_name": "Degree Referral Number", "attribute_value_mlt": [{"subitem_dissertationnumber": "甲第23号"}]}, "item_10006_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.15102/1394.00000700", "subitem_identifier_reg_type": "JaLC"}]}, "item_10006_rights_13": {"attribute_name": "Copyright Information", "attribute_value_mlt": [{"subitem_rights": "© 2018 The Author "}]}, "item_10006_text_24": {"attribute_name": "Exam Date", "attribute_value_mlt": [{"subitem_text_value": "2018-10-03"}]}, "item_10006_version_type_18": {"attribute_name": "Version Format", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-12-05"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Full_Text.pdf", "filesize": [{"value": "3.9 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 3900000.0, "url": {"label": "Full Text", "objectType": "fulltext", "url": "https://oist.repo.nii.ac.jp/record/764/files/Full_Text.pdf"}, "version_id": "5ded06c6-e783-4e4b-8d74-82eddc6a2c1f"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-12-05"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "Final_Exam_Abstract.pdf", "filesize": [{"value": "43.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 43000.0, "url": {"label": "Final Exam Abstract", "objectType": "abstract", "url": "https://oist.repo.nii.ac.jp/record/764/files/Final_Exam_Abstract.pdf"}, "version_id": "45e0de4c-862f-4742-8d8a-481722a61b4e"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "自発行動の性質と起点:マウスにおける心理行動学的発達と神経群の活動による考察", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "自発行動の性質と起点:マウスにおける心理行動学的発達と神経群の活動による考察", "subitem_title_language": "ja"}, {"subitem_title": "Nature and source of animal spontaneous behaviors: Insights from psychobehavioral development and neuronal population dynamics in mice", "subitem_title_language": "en"}]}, "item_type_id": "10006", "owner": "22", "path": ["84"], "permalink_uri": "https://doi.org/10.15102/1394.00000700", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-12-05"}, "publish_date": "2018-12-05", "publish_status": "0", "recid": "764", "relation": {}, "relation_version_is_last": true, "title": ["自発行動の性質と起点:マウスにおける心理行動学的発達と神経群の活動による考察"], "weko_shared_id": -1}
自発行動の性質と起点:マウスにおける心理行動学的発達と神経群の活動による考察
https://doi.org/10.15102/1394.00000700
https://doi.org/10.15102/1394.0000070009f3fa2a-cd11-4051-b5cc-a3980dfcb690
名前 / ファイル | ライセンス | アクション |
---|---|---|
Full Text (3.9 MB)
|
|
|
Final Exam Abstract (43.0 kB)
|
|
Item type | 学位論文 / Thesis or Dissertation(1) | |||||||
---|---|---|---|---|---|---|---|---|
公開日 | 2018-12-05 | |||||||
タイトル | ||||||||
言語 | ja | |||||||
タイトル | 自発行動の性質と起点:マウスにおける心理行動学的発達と神経群の活動による考察 | |||||||
タイトル | ||||||||
言語 | en | |||||||
タイトル | Nature and source of animal spontaneous behaviors: Insights from psychobehavioral development and neuronal population dynamics in mice | |||||||
言語 | ||||||||
言語 | eng | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||
資源タイプ | doctoral thesis | |||||||
ID登録 | ||||||||
ID登録 | 10.15102/1394.00000700 | |||||||
ID登録タイプ | JaLC | |||||||
アクセス権 | ||||||||
アクセス権 | open access | |||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
著者 (英) |
Lee, Ray Xin
× Lee, Ray Xin
|
|||||||
抄録 | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | Awake animals switch between different behavioral states irregularly even in a homogenous and steady environment, especially obvious outside from any behavioral task when they are free to voluntarily behave. These irregular but structured patterns have been taken as a representation of internal states such as emotion, and are believed to represent underlying background brain activity and its dynamics. To date, the nature and source of animal spontaneous behaviors remain as a major conceptual challenge to academia, due to the lack of approaches to systematically and quantitatively examine this fundamental process. To achieve insights about the neural substrate of animal spontaneous behaviors, the research was conducted in two directions: (i) To interpret previously challenging and inconclusive behavioral development by re-evaluating spontaneous behaviors that represent emotionality, centered on the study of PTSD (post-traumatic stress disorder)-like internal psychological development in laboratory mice; (ii) To demonstrate a driving and control principle explaining fine-scale and global observations of neuronal and behavioral dynamics in spontaneously behaving mice, by two-photon calcium imaging of neuronal populations across cerebral cortical layers and areas. The results from these investigations provide the first system-level view of experimentally disentangled components, processes, and determinants explaining the nature and source of animal spontaneous behaviors. | |||||||
口頭試問日 | ||||||||
2018-10-03 | ||||||||
学位授与年月日 | ||||||||
学位授与年月日 | 2018-11-30 | |||||||
学位名 | ||||||||
学位名 | Doctor of Philosophy | |||||||
学位授与番号 | ||||||||
学位授与番号 | 甲第23号 | |||||||
学位授与機関 | ||||||||
学位授与機関識別子Scheme | kakenhi | |||||||
学位授与機関識別子 | 38005 | |||||||
学位授与機関名 | Okinawa Institute of Science and Technology Graduate University | |||||||
著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
権利 | ||||||||
権利情報 | © 2018 The Author |