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The habu genome reveals accelerated evolution of venom protein genes
https://oist.repo.nii.ac.jp/records/874
https://oist.repo.nii.ac.jp/records/874c8b41b34-230c-4c17-87f8-d2bf71a13601
名前 / ファイル | ライセンス | アクション |
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Shibata-2018-The habu genome reveals accelerat (1.6 MB)
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Creative Commons
Attribution 4.0 International (https://creativecommons.org/licenses/by/4.0/) |
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-05-16 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The habu genome reveals accelerated evolution of venom protein genes | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Shibata, Hiroki
× Shibata, Hiroki× Chijiwa, Takahito× Oda-Ueda, Naoko× Nakamura, Hitomi× Yamaguchi, Kazuaki× Hattori, Shousaku× Matsubara, Kazumi× Matsuda, Yoichi× Yamashita, Akifumi× Isomoto, Akiko× Mori, Kazuki× Tashiro, Kosuke× Kuhara, Satoru× Yamasaki, Shinichi× Fujie, Manabu× Goto, Hiroki× Koyanagi, Ryo× Takeuchi, Takeshi× Fukumaki, Yasuyuki× Ohno, Motonori× Shoguchi, Eiichi× Hisata, Kanako× Satoh, Noriyuki× Ogawa, Tomohisa |
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書誌情報 |
en : Scientific Reports 巻 8, 号 1, p. 11300, 発行日 2018-07-26 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Evolution of novel traits is a challenging subject in biological research. Several snake lineages developed elaborate venom systems to deliver complex protein mixtures for prey capture. To understand mechanisms involved in snake venom evolution, we decoded here the ~1.4-Gb genome of a habu, Protobothrops flavoviridis. We identified 60 snake venom protein genes (SV) and 224 non-venom paralogs (NV), belonging to 18 gene families. Molecular phylogeny reveals early divergence of SV and NV genes, suggesting that one of the four copies generated through two rounds of whole-genome duplication was modified for use as a toxin. Among them, both SV and NV genes in four major components were extensively duplicated after their diversification, but accelerated evolution is evident exclusively in the SV genes. Both venom-related SV and NV genes are significantly enriched in microchromosomes. The present study thus provides a genetic background for evolution of snake venom composition. | |||||
出版者 | ||||||
出版者 | Nature Research | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2045-2322 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/30050104 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1038/s41598-018-28749-4 | |||||
権利 | ||||||
権利情報 | © 2018 The Author(s). | |||||
情報源 | ||||||
関連名称 | http://creativecommons.org/licenses/by/4.0/ | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.nature.com/articles/s41598-018-28749-4 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |