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Aptamer-based and aptazyme-based riboswitches in mammalian cells
https://oist.repo.nii.ac.jp/records/1221
https://oist.repo.nii.ac.jp/records/122142226977-ae96-412c-98b8-668468ded06b
名前 / ファイル | ライセンス | アクション |
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Yokobayashi-2019-Aptamer-based and aptazyme-ba (442.1 kB)
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Creative Commons Attribution 4.0 International(https://creativecommons.org/licenses/by/4.0/)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-03-04 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Aptamer-based and aptazyme-based riboswitches in mammalian cells | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Yokobayashi, Yohei
× Yokobayashi, Yohei |
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書誌情報 |
en : Current Opinion in Chemical Biology 巻 52, p. 72-78, 発行日 2019-06-22 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Molecular recognition by RNA aptamers has been exploited to control gene expression in response to small molecules in mammalian cells. These mammalian synthetic riboswitches offer attractive features such as small genetic size and lower risk of immunological complications compared to protein-based transcriptional gene switches. The diversity of gene regulatory mechanisms that involve RNA has also inspired the development of mammalian riboswitches that harness various regulatory mechanisms. In this report, recent advances in synthetic riboswitches that function in mammalian cells are reviewed focusing on the regulatory mechanisms they exploit such as mRNA degradation, microRNA processing, and programmed ribosomal frameshifting. | |||||
出版者 | ||||||
出版者 | ELSEVIER | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1367-5931 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/31238268 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1016/j.cbpa.2019.05.018 | |||||
権利 | ||||||
権利情報 | ©2019 The Author | |||||
情報源 | ||||||
関連名称 | https://creativecommons.org/licenses/by/4.0/ | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.sciencedirect.com/science/article/pii/S1367593118302023 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |