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New cytotoxic cembranolides from an Okinawan soft coral, Lobophytum sp.
https://oist.repo.nii.ac.jp/records/1320
https://oist.repo.nii.ac.jp/records/1320aea2f02a-8c56-463f-aaa0-89f848881bc1
名前 / ファイル | ライセンス | アクション |
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1-s2.0-S0367326X1930718X-main-1 (872.5 kB)
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International(https://creativecommons.org/licenses/by-nc-nd/4.0/)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-03-24 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | New cytotoxic cembranolides from an Okinawan soft coral, Lobophytum sp. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Roy, Prodip K.
× Roy, Prodip K.× Roy, Sona× Ueda, Katsuhiro |
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書誌情報 |
en : Fitoterapia 巻 136, p. 104162, 発行日 2019-05-07 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Three new cembranolides (1-3) were isolated from an Okinawan soft coral, Lobophytum sp., together with the known cembranolide diterpenoids (4-9). Their structures were determined by extensive analysis of spectroscopic data (1D and 2D NMR, IR, and MS), molecular modeling, and comparison with data reported elsewhere. All compounds contain an alpha-methylene-gamma-lactone ring adjacent to a cembrane, and some of them (1, 6-8) have an epoxide ring as well. The new metabolites were evaluated for cytotoxicity against HeLa, A459, B16-F10, and RAW 264.7 cells and anti-inflammatory effect in LPS-stimulated inflammatory RAW 264.7 macrophage cells. | |||||
出版者 | ||||||
出版者 | Elsevier | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0367-326X | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/31075489 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1016/j.fitote.2019.05.001 | |||||
権利 | ||||||
権利情報 | © 2019 Elsevier B.V. | |||||
情報源 | ||||||
関連名称 | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
関連サイト | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.fitote.2019.05.001 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |