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Identification, cloning and heterologous expression of biosynthetic gene cluster for desertomycin
https://oist.repo.nii.ac.jp/records/1664
https://oist.repo.nii.ac.jp/records/16640372618c-ed51-4807-97d3-5c94790250bd
名前 / ファイル | ライセンス | アクション |
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Desertomycin_Revised_manuscript_OIST_repository (434.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-08-05 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Identification, cloning and heterologous expression of biosynthetic gene cluster for desertomycin | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Antibiotics | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Biosynthesis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Hashimoto, Takuya
× Hashimoto, Takuya× Kozone, Ikuko× Hashimoto, Junko× Suenaga, Hikaru× Fujie, Manabu× Satoh, Noriyuki× Ikeda, Haruo× Shin-ya, Kazuo |
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書誌情報 |
en : The Journal of Antibiotics 巻 73, 号 9, p. 650-654, 発行日 2020-05-26 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | From our in-house microbial genome database of secondary metabolite producers, we identified a candidate biosynthetic gene cluster for desertomycin from Streptomyces nobilis JCM4274. We report herein the cloning of the 127-kb entire gene cluster for desertomycin biosynthesis using bacterial artificial chromosome vector. The entire biosynthetic gene cluster for desertomycin was introduced in the heterologous host, Streptomyces lividans TK23, with an average yield of more than 130 mg l(-1). | |||||
出版者 | ||||||
出版者 | nature research | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0021-8820 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1881-1469 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/32457441 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1038/s41429-020-0319-0 | |||||
関連サイト | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1038/s41429-020-0319-0 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |