WEKO3
アイテム
{"_buckets": {"deposit": "80f8c981-8605-4a7f-8d02-d6f6eb4175e4"}, "_deposit": {"created_by": 30, "id": "1731", "owners": [30], "pid": {"revision_id": 0, "type": "depid", "value": "1731"}, "status": "published"}, "_oai": {"id": "oai:oist.repo.nii.ac.jp:00001731", "sets": ["191"]}, "author_link": ["10427", "10430", "10429", "10428"], "item_10001_biblio_info_7": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2020-09-18", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "556175", "bibliographicVolumeNumber": "13", "bibliographic_titles": [{}, {"bibliographic_title": "Frontiers in Molecular Neuroscience", "bibliographic_titleLang": "en"}]}]}, "item_10001_creator_3": {"attribute_name": "Author", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Guillaud, Laurent"}], "nameIdentifiers": [{"nameIdentifier": "10427", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "El-Agamy, Sara Emad"}], "nameIdentifiers": [{"nameIdentifier": "10428", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Otsuki, Miki"}], "nameIdentifiers": [{"nameIdentifier": "10429", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Terenzio, Marco"}], "nameIdentifiers": [{"nameIdentifier": "10430", "nameIdentifierScheme": "WEKO"}]}]}, "item_10001_description_5": {"attribute_name": "Abstract", "attribute_value_mlt": [{"subitem_description": "Neurons are highly polarized cells with an elongated axon that extends far away from the cell body. To maintain their homeostasis, neurons rely extensively on axonal transport of membranous organelles and other molecular complexes. Axonal transport allows for spatio-temporal activation and modulation of numerous molecular cascades, thus playing a central role in the establishment of neuronal polarity, axonal growth and stabilization, and synapses formation. Anterograde and retrograde axonal transport are supported by various molecular motors, such as kinesins and dynein, and a complex microtubule network. In this review article, we will primarily discuss the molecular mechanisms underlying anterograde axonal transport and its role in neuronal development and maturation,including the establishment of functional synaptic connections.We will then provide an overview of the molecular and cellular perturbations that affect axonal transport and are often associated with axonal degeneration. Lastly, we will relate our current understanding of the role of axonal trafficking concerning anterograde trafficking of mRNA and its involvement in the maintenance of the axonal compartment and disease.", "subitem_description_type": "Other"}]}, "item_10001_publisher_8": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_publisher": "Frontiers Media S.A."}]}, "item_10001_relation_13": {"attribute_name": "PubMedNo.", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "info:pmid/33071754", "subitem_relation_type_select": "PMID"}}]}, "item_10001_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "info:doi/10.3389/fnmol.2020.556175", "subitem_relation_type_select": "DOI"}}]}, "item_10001_relation_17": {"attribute_name": "Related site", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.frontiersin.org/articles/10.3389/fnmol.2020.556175/full", "subitem_relation_type_select": "URI"}}]}, "item_10001_rights_15": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_rights": "© 2020 Guillaud, El-Agamy, Otsuki and Terenzio."}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1662-5099", "subitem_source_identifier_type": "ISSN"}]}, "item_10001_version_type_20": {"attribute_name": "Author\u0027s flag", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-10-23"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Guillaud-2020-Anterograde Axonal Transport in.pdf", "filesize": [{"value": "2.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Creative Commons Attribution 4.0 International(https://creativecommons.org/licenses/by/4.0/)", "licensetype": "license_free", "mimetype": "application/pdf", "size": 2300000.0, "url": {"label": "Guillaud-2020-Anterograde Axonal Transport in", "url": "https://oist.repo.nii.ac.jp/record/1731/files/Guillaud-2020-Anterograde Axonal Transport in.pdf"}, "version_id": "0fea4f12-a4c5-4010-8728-4fd6ad6cfc9a"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "kinesin", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "intracellular transport", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "axon growth", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "synaptogenesis", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "neurodegeneration", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "local translation", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "liquid phase separation", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Anterograde Axonal Transport in Neuronal Homeostasis and Disease", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Anterograde Axonal Transport in Neuronal Homeostasis and Disease", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "30", "path": ["191"], "permalink_uri": "https://oist.repo.nii.ac.jp/records/1731", "pubdate": {"attribute_name": "公開日", "attribute_value": "2020-10-23"}, "publish_date": "2020-10-23", "publish_status": "0", "recid": "1731", "relation": {}, "relation_version_is_last": true, "title": ["Anterograde Axonal Transport in Neuronal Homeostasis and Disease"], "weko_shared_id": 30}
Anterograde Axonal Transport in Neuronal Homeostasis and Disease
https://oist.repo.nii.ac.jp/records/1731
https://oist.repo.nii.ac.jp/records/17310f0791c9-ea91-490a-9e30-bcf10cff7233
名前 / ファイル | ライセンス | アクション |
---|---|---|
Guillaud-2020-Anterograde Axonal Transport in (2.3 MB)
|
Creative Commons Attribution 4.0 International(https://creativecommons.org/licenses/by/4.0/)
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2020-10-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Anterograde Axonal Transport in Neuronal Homeostasis and Disease | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | kinesin | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | intracellular transport | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | axon growth | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | synaptogenesis | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | neurodegeneration | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | local translation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | liquid phase separation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Guillaud, Laurent
× Guillaud, Laurent× El-Agamy, Sara Emad× Otsuki, Miki× Terenzio, Marco |
|||||
書誌情報 |
en : Frontiers in Molecular Neuroscience 巻 13, p. 556175, 発行日 2020-09-18 |
|||||
抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Neurons are highly polarized cells with an elongated axon that extends far away from the cell body. To maintain their homeostasis, neurons rely extensively on axonal transport of membranous organelles and other molecular complexes. Axonal transport allows for spatio-temporal activation and modulation of numerous molecular cascades, thus playing a central role in the establishment of neuronal polarity, axonal growth and stabilization, and synapses formation. Anterograde and retrograde axonal transport are supported by various molecular motors, such as kinesins and dynein, and a complex microtubule network. In this review article, we will primarily discuss the molecular mechanisms underlying anterograde axonal transport and its role in neuronal development and maturation,including the establishment of functional synaptic connections.We will then provide an overview of the molecular and cellular perturbations that affect axonal transport and are often associated with axonal degeneration. Lastly, we will relate our current understanding of the role of axonal trafficking concerning anterograde trafficking of mRNA and its involvement in the maintenance of the axonal compartment and disease. | |||||
出版者 | ||||||
出版者 | Frontiers Media S.A. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1662-5099 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/33071754 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.3389/fnmol.2020.556175 | |||||
権利 | ||||||
権利情報 | © 2020 Guillaud, El-Agamy, Otsuki and Terenzio. | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.frontiersin.org/articles/10.3389/fnmol.2020.556175/full | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |