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Mechanisms of protein evolution
https://oist.repo.nii.ac.jp/records/2717
https://oist.repo.nii.ac.jp/records/2717b1c675f6-2b64-4391-a0d6-2bf18e963a77
名前 / ファイル | ライセンス | アクション |
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20220511_Mechanisms of protein evolution_clea (1.7 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2022-07-27 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Mechanisms of protein evolution | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Jayaraman, Vijay
× Jayaraman, Vijay× Toledo‐Patiño, Saacnicteh× Noda‐García, Lianet× Laurino, Paola |
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書誌情報 |
en : Protein Science 巻 31, 号 7, p. e4362, 発行日 2022-06-22 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | How do proteins evolve? How do changes in sequence mediate changes in protein structure, and in turn in function? This question has multiple angles, ranging from biochemistry and biophysics to evolutionary biology. This review provides a brief integrated view of some key mechanistic aspects of protein evolution. First, we explain how protein evolution is primarily driven by randomly acquired genetic mutations and selection for function, and how these mutations can even give rise to completely new folds. Then, we also comment on how phenotypic protein variability, including promiscuity, transcriptional and translational errors, may also accelerate this process, possibly via “plasticity-first” mechanisms. Finally, we highlight open questions in the field of protein evolution, with respect to the emergence of more sophisticated protein systems such as protein complexes, pathways, and the emergence of pre-LUCA enzymes. | |||||
出版者 | ||||||
出版者 | John Wiley & Sons, Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0961-8368 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1469-896X | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1002/pro.4362 | |||||
権利 | ||||||
権利情報 | © 2022 The Author(s) | |||||
権利 | ||||||
権利情報 | This is the peer reviewed version of the following article: ayaraman, V, Toledo-Patiño, S, Noda-García, L, Laurino, P. Mechanisms of protein evolution. Protein Science. 2022; 31( 7):e4362. https://doi.org/10.1002/pro.4362, which has been published in final form at https://onlinelibrary.wiley.com/doi/10.1002/pro.4362. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://onlinelibrary.wiley.com/doi/10.1002/pro.4362 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |