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巨大シナプス前末端微小管の機能的役割
https://doi.org/10.15102/1394.00000732
https://doi.org/10.15102/1394.000007324f0f8be3-86d0-4876-9ba7-f6c303c479d4
名前 / ファイル | ライセンス | アクション |
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Abstract (6.6 kB)
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Final Exam Abstract (42.9 kB)
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Full text (3.5 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||||
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公開日 | 2019-02-04 | |||||||
タイトル | ||||||||
言語 | ja | |||||||
タイトル | 巨大シナプス前末端微小管の機能的役割 | |||||||
タイトル | ||||||||
言語 | en | |||||||
タイトル | Functional roles of microtubules in a giant presynaptic terminal | |||||||
言語 | ||||||||
言語 | eng | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||
資源タイプ | doctoral thesis | |||||||
ID登録 | ||||||||
ID登録 | 10.15102/1394.00000732 | |||||||
ID登録タイプ | JaLC | |||||||
アクセス権 | ||||||||
アクセス権 | open access | |||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
著者 (英) |
Ananda Babu, Lashmi Piriya
× Ananda Babu, Lashmi Piriya
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抄録 | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | The functional roles of cytoskeletal elements actin and microtubule are well established in various cellular processes. However, their role in axon terminals is still unclear. Here, I started my thesis study by questioning the role of actin filaments at the calyx of Held presynaptic terminals in developing rats before and after hearing onset. Having observed that actin filaments are involved in synaptic vesicle recruitment in pre-hearing rats, but not in post-hearing rats, I then proceeded to address the functional roles of the other cytoskeletal element, namely microtubules in rats after hearing onset. I have used a combination of tools to address both the functional and morphological aspects. I found that both cytoskeletal elements play significant roles in regulating synaptic transmission. | |||||||
口頭試問日 | ||||||||
2018-03-20 | ||||||||
学位授与年月日 | ||||||||
学位授与年月日 | 2018-05-17 | |||||||
学位名 | ||||||||
学位名 | Doctor of Philosophy | |||||||
学位授与番号 | ||||||||
学位授与番号 | 甲第15号 | |||||||
学位授与機関 | ||||||||
学位授与機関識別子Scheme | kakenhi | |||||||
学位授与機関識別子 | 38005 | |||||||
学位授与機関名 | Okinawa Institute of Science and Technology Graduate University | |||||||
著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
権利 | ||||||||
権利情報 | © 2018 The Author |