@article{oai:oist.repo.nii.ac.jp:00001210, author = {Mang, Dingze and Zhang, Shijin and Wu, Xia and Hu, Xunwu and Mochizuki, Toshiaki and Li, Guanying and Zhang, Ye}, issue = {43}, journal = {Chemical Communications}, month = {May}, note = {We designed and synthesized homochiral-peptide-based boron diketonate complexes. Co-administration of the two stereoisomers in cancer cells led to molecular assembly targeting both the plasma membrane and the lysosomes mediated via membrane-bonded enzymes. The dual-targeted-assembly generates a synergistic anticancer effect with amplified cancer spheroid toxicity and enhanced inhibition efficacy on cancer cell migration.}, pages = {6126--6129}, title = {Enzyme-mediated dual-targeted-assembly realizes a synergistic anticancer effect}, volume = {55}, year = {2019} }