{"created":"2023-06-26T11:00:47.620615+00:00","id":1384,"links":{},"metadata":{"_buckets":{"deposit":"b7466607-8d98-403a-b69c-b640850fdfc2"},"_deposit":{"created_by":28,"id":"1384","owners":[28],"pid":{"revision_id":0,"type":"depid","value":"1384"},"status":"published"},"_oai":{"id":"oai:oist.repo.nii.ac.jp:00001384","sets":["6:61"]},"author_link":["8392","8390","8386","8391","8385","8387","8393","8389","8388"],"item_10001_biblio_info_7":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-11-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"10","bibliographicPageStart":"6","bibliographicVolumeNumber":"22","bibliographic_titles":[{},{"bibliographic_title":"Organic Letters","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"Author","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Zhang, Dongxin"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chen, Yan"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Cai, Hu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yin, Lei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Zhong, Junchao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Man, Jingjing"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Zhang, Qian-Feng"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Bethi, Venkati"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanaka, Fujie"}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Direct asymmetric synthesis of δ-hydroxy-β-ketoesters was accomplished via regio- and enantioselective aldol reactions of β-ketoesters with isatins catalyzed by cinchona alkaloid thiourea derivatives. The C–C bond formation of the reactions occurred only at the γ-position of the β-ketoesters. Reaction progress monitoring and product stability analyses under the conditions that included the catalyst indicated that the γ-position reaction products were formed kinetically. Various δ-hydroxy-β-ketoesters bearing 3-alkyl-3-hydroxyoxindole cores relevant to the development of bioactive molecules were synthesized.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"American Chemical Society"}]},"item_10001_relation_13":{"attribute_name":"PubMedNo.","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:pmid/31746616","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1021/acs.orglett.9b03527","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"Related site","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pubs.acs.org/doi/abs/10.1021/acs.orglett.9b03527","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2019 American Chemical Society"},{"subitem_rights":"This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://pubs.acs.org/doi/abs/10.1021/acs.orglett.9b03527."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1523-7060","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"1523-7052","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"Author's flag","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-11-20"}],"displaytype":"detail","filename":"ketoester 2nd  revision 20191114 clean.pdf","filesize":[{"value":"838.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ketoester 2nd  revision 20191114 clean","url":"https://oist.repo.nii.ac.jp/record/1384/files/ketoester 2nd  revision 20191114 clean.pdf"},"version_id":"3e92030f-972b-4776-afd0-9391d7d07868"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Direct Catalytic Asymmetric Synthesis of Oxindole-Derived δ-Hydroxy-β-ketoesters by Aldol Reactions","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Direct Catalytic Asymmetric Synthesis of Oxindole-Derived δ-Hydroxy-β-ketoesters by Aldol Reactions","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"28","path":["61"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-04-22"},"publish_date":"2020-04-22","publish_status":"0","recid":"1384","relation_version_is_last":true,"title":["Direct Catalytic Asymmetric Synthesis of Oxindole-Derived δ-Hydroxy-β-ketoesters by Aldol Reactions"],"weko_creator_id":"28","weko_shared_id":28},"updated":"2023-06-26T11:50:17.385075+00:00"}