{"created":"2023-06-26T11:00:01.919339+00:00","id":200,"links":{},"metadata":{"_buckets":{"deposit":"f9217623-810a-499b-8e7f-a82134e30c9a"},"_deposit":{"created_by":27,"id":"200","owners":[27],"pid":{"revision_id":0,"type":"depid","value":"200"},"status":"published"},"_oai":{"id":"oai:oist.repo.nii.ac.jp:00000200","sets":["6:49"]},"author_link":["334","333","335","332","331"],"item_10001_biblio_info_7":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-02-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1713","bibliographicPageStart":"20150480","bibliographicVolumeNumber":"372","bibliographic_titles":[{},{"bibliographic_title":"Philosophical Transactions of the Royal Society B","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"Author","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Holland, Peter W. H."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Marletaz, Ferdinand"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeso, Ignacio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Dunwell, Thomas L."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Paps, Jordi"}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Gene duplications and gene losses have been frequent events in the evolution of animal genomes, with the balance between these two dynamic processes contributing to major differences in gene number between species. After gene duplication, it is common for both daughter genes to accumulate sequence change at approximately equal rates. In some cases, however, the accumulation of sequence change is highly uneven with one copy radically diverging from its paralogue. Such ‘asymmetric evolution’ seems commoner after tandem gene duplication than after whole-genome duplication, and can generate substantially novel genes. We describe examples of asymmetric evolution in duplicated homeobox genes of moths, molluscs and mammals, in each case generating new homeobox genes that were recruited to novel developmental roles. The prevalence of asymmetric divergence of gene duplicates has been underappreciated, in part, because the origin of highly divergent genes can be difficult to resolve using standard phylogenetic methods.This article is part of the themed issue ‘Evo-devo in the genomics era, and the origins of morphological diversity’.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"The Royal Society"}]},"item_10001_relation_13":{"attribute_name":"PubMedNo.","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:pmid/27994121","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1098/rstb.2015.0480","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"Related site","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://rstb.royalsocietypublishing.org/content/372/1713/20150480","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2016 The Authors."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0962-8436  ","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"1471-2970 ","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"Author's flag","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"20150480.full.pdf","filesize":[{"value":"885.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"20150480.full","url":"https://oist.repo.nii.ac.jp/record/200/files/20150480.full.pdf"},"version_id":"c11ed931-b3ee-4bba-b24a-8762b24c6e06"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"New genes from old: asymmetric divergence of gene duplicates and the evolution of development","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"New genes from old: asymmetric divergence of gene duplicates and the evolution of development"},{"subitem_title":"New genes from old: asymmetric divergence of gene duplicates and the evolution of development","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"27","path":["49"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-28"},"publish_date":"2017-12-28","publish_status":"0","recid":"200","relation_version_is_last":true,"title":["New genes from old: asymmetric divergence of gene duplicates and the evolution of development"],"weko_creator_id":"27","weko_shared_id":27},"updated":"2023-06-26T12:10:49.491466+00:00"}