{"created":"2023-06-26T11:00:01.986298+00:00","id":201,"links":{},"metadata":{"_buckets":{"deposit":"4a4b013c-3e67-4cdf-b61e-946c4b88113b"},"_deposit":{"created_by":27,"id":"201","owners":[27],"pid":{"revision_id":0,"type":"depid","value":"201"},"status":"published"},"_oai":{"id":"oai:oist.repo.nii.ac.jp:00000201","sets":["6:51"]},"author_link":["346","348","349","247"],"item_10001_biblio_info_7":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-03-23","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4","bibliographicVolumeNumber":"3","bibliographic_titles":[{},{"bibliographic_title":"Zoological Letters","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"Author","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Inoue, Jun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yasuoka, Yuuri"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takahashi, Hiroki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Satoh, Noriyuki"}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Background: The T-box family transcription-factor gene, Brachyury, has two expression domains with discrete\nfunctions during animal embryogenesis. The primary domain, associated with the blastopore, is shared by most\nmetazoans, while the secondary domain, involved in the notochord, is specific to chordates. In most animals,\nBrachyury is present in a single copy, but in cephalochordates, the most basal of the chordates, the gene is present\nin two copies, suggesting allotment of the two domains to each of the duplicates.\nResults: In order to clarify whether Brachyury duplication occurred in the common ancestor of chordates after\nwhich one of duplicates was lost in the urochordate and vertebrate lineages, we estimated phylogenetic\nrelationships of Brachyury genes and examined the synteny of a Brachyury-containing genomic region of\ndeuterostomes with decoded genomes. The monophyletic origin of tandemly arranged Brachyury genes of\ncephalochordates indicates that the tandem duplication occurred in the cephalochordate lineage, but not in the\nchordate ancestor.\nConclusions: Our results thus suggest that, in the common ancestor of chordates, a single copy of Brachyury\nacquired two expression domains and that the duplication was not involved in the acquisition of the notochord.\nHowever, in relation to regulatory mechanisms, both possibilities—namely a single copy with two domains and\ntwo copies with different domains—should be considered in future studies of Brachyury.","subitem_description_type":"Other"}]},"item_10001_relation_13":{"attribute_name":"PubMedNo.","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:pmid/28344820 ","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1186/s40851-017-0064-9","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"Related site","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://zoologicalletters.biomedcentral.com/articles/10.1186/s40851-017-0064-9","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2017 The Author(s). "}]},"item_10001_version_type_20":{"attribute_name":"Author's flag","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-12"}],"displaytype":"detail","filename":"Inoue et al Zoological letters 2017.pdf.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","license_note":"Creative Commons Attribution 4.0 International  \n(http://creativecommons.org/licenses/by/4.0/)","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Inoue et al Zoological letters 2017","url":"https://oist.repo.nii.ac.jp/record/201/files/Inoue et al Zoological letters 2017.pdf.pdf"},"version_id":"25f5534a-a19f-4b3e-a62b-4be9de9d818d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The chordate ancestor possessed a single copy of the Brachyury gene for notochord acquisition","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The chordate ancestor possessed a single copy of the Brachyury gene for notochord acquisition"},{"subitem_title":"The chordate ancestor possessed a single copy of the Brachyury gene for notochord acquisition","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"27","path":["51"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-28"},"publish_date":"2017-12-28","publish_status":"0","recid":"201","relation_version_is_last":true,"title":["The chordate ancestor possessed a single copy of the Brachyury gene for notochord acquisition"],"weko_creator_id":"27","weko_shared_id":27},"updated":"2023-06-26T12:09:20.677171+00:00"}