{"created":"2023-06-26T11:01:48.754164+00:00","id":2567,"links":{},"metadata":{"_buckets":{"deposit":"1e238ddb-327d-4a3d-a83d-0c7b2ef4d1cb"},"_deposit":{"created_by":32,"id":"2567","owners":[32],"pid":{"revision_id":0,"type":"depid","value":"2567"},"status":"published"},"_oai":{"id":"oai:oist.repo.nii.ac.jp:00002567","sets":["6:49"]},"author_link":["16744","16746","16740","16745","16748","16749","16751","16739","16750","16742","16747","16741","16743"],"item_10001_biblio_info_7":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-02-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageStart":"eabi5884","bibliographicVolumeNumber":"8","bibliographic_titles":[{},{"bibliographic_title":"Science Advances","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"Author","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Simakov, Oleg"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Bredeson, Jessen"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Berkoff, Kodiak"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Marletaz, Ferdinand"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mitros, Therese"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Schultz, Darrin T."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"O’Connell, Brendan L."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Dear, Paul"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Martinez, Daniel E."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Steele, Robert E."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Green, Richard E."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"David, Charles N."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Rokhsar, Daniel S."}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Animal genomes show networks of deeply conserved gene linkages whose phylogenetic scope and chromosomal context remain unclear. Here, we report chromosome-scale conservation of synteny among bilaterians, cnidarians, and sponges and use comparative analysis to reconstruct ancestral chromosomes across major animal groups. Comparisons among diverse metazoans reveal the processes of chromosome evolution that produced contemporary karyotypes from their Precambrian progenitors. On the basis of these findings, we introduce a simple algebraic representation of chromosomal change and use it to establish a unified systematic framework for metazoan chromosome evolution. We find that fusion-with-mixing, a previously unappreciated mode of chromosome change, has played a central role. We find that relicts of several metazoan chromosomal units are preserved in unicellular eukaryotes. These conserved pre-metazoan linkages include the chromosomal unit that encodes the most diverse set of metazoan homeobox genes, suggesting a candidate genomic context for the early diversification of this key gene family.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"American Association for the Advancement of Science"}]},"item_10001_relation_13":{"attribute_name":"PubMedNo.","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:pmid/35108053","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1126/sciadv.abi5884","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"Related site","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.science.org/doi/10.1126/sciadv.abi5884","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2022 The Author(s), some rights reserved; exclusive licensee American Association for the Advancement of Science. "}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2375-2548","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"Author's flag","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-17"}],"displaytype":"detail","filename":"sciadv.abi5884.pdf","filesize":[{"value":"2.6 MB"}],"format":"application/pdf","license_note":"Creative Commons Attribution-NonCommercial 4.0 International(https://creativecommons.org/licenses/by-nc/4.0/)","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"sciadv.abi5884","url":"https://oist.repo.nii.ac.jp/record/2567/files/sciadv.abi5884.pdf"},"version_id":"14500c40-d975-4486-9949-f057e386f1c2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Deeply conserved synteny and the evolution of metazoan chromosomes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Deeply conserved synteny and the evolution of metazoan chromosomes","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"32","path":["49"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-17"},"publish_date":"2022-02-17","publish_status":"0","recid":"2567","relation_version_is_last":true,"title":["Deeply conserved synteny and the evolution of metazoan chromosomes"],"weko_creator_id":"32","weko_shared_id":32},"updated":"2023-06-26T11:28:39.404212+00:00"}