{"created":"2023-06-26T11:02:02.349172+00:00","id":2807,"links":{},"metadata":{"_buckets":{"deposit":"ab5f1a34-2277-4e94-a1e0-0dd0fb113d38"},"_deposit":{"created_by":31,"id":"2807","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"2807"},"status":"published"},"_oai":{"id":"oai:oist.repo.nii.ac.jp:00002807","sets":["6:68"]},"author_link":["18026","18027"],"item_10001_biblio_info_7":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-08-01","bibliographicIssueDateType":"Issued"},"bibliographicVolumeNumber":"16","bibliographic_titles":[{},{"bibliographic_title":"Frontiers in Computational Neuroscience","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"Author","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ponzi, Adam"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Wickens, Jeff"}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Control of the timing of behavior is thought to require the basal ganglia (BG) and BG pathologies impair performance in timing tasks. Temporal interval discrimination depends on the ramping activity of medium spiny neurons (MSN) in the main BG input structure, the striatum, but the underlying mechanisms driving this activity are unclear. Here, we combine an MSN dynamical network model with an action selection system applied to an interval discrimination task. We find that when network parameters are appropriate for the striatum so that slowly fluctuating marginally stable dynamics are intrinsically generated, up and down ramping populations naturally emerge which enable significantly above chance task performance. We show that emergent population activity is in very good agreement with empirical studies and discuss how MSN network dysfunction in disease may alter temporal perception.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Frontiers Media"}]},"item_10001_relation_13":{"attribute_name":"PubMedNo.","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:pmid/35978564","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.3389/fncom.2022.902741","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"Related site","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.frontiersin.org/articles/10.3389/fncom.2022.902741/full","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2022 The Author(s)."},{"subitem_rights":"This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1662-5188","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"Author's flag","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-10-04"}],"displaytype":"detail","filename":"fncom-16-902741.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","license_note":"CC BY 4.0\nCreative Commons Attribution 4.0 International (https://creativecommons.org/licenses/by/4.0/)","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"fncom-16-902741","url":"https://oist.repo.nii.ac.jp/record/2807/files/fncom-16-902741.pdf"},"version_id":"09d70790-4c2c-4a37-be74-f756130f70b3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"interval discrimination","subitem_subject_scheme":"Other"},{"subitem_subject":"computational model","subitem_subject_scheme":"Other"},{"subitem_subject":"striatum","subitem_subject_scheme":"Other"},{"subitem_subject":"basal ganglia","subitem_subject_scheme":"Other"},{"subitem_subject":"neural ramping","subitem_subject_scheme":"Other"},{"subitem_subject":"network dynamics","subitem_subject_scheme":"Other"},{"subitem_subject":"temporal estimation","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Ramping activity in the striatum","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Ramping activity in the striatum","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"31","path":["68"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-10-04"},"publish_date":"2022-10-04","publish_status":"0","recid":"2807","relation_version_is_last":true,"title":["Ramping activity in the striatum"],"weko_creator_id":"31","weko_shared_id":31},"updated":"2023-06-26T11:23:36.572490+00:00"}