{"created":"2023-06-26T11:00:13.251895+00:00","id":637,"links":{},"metadata":{"_buckets":{"deposit":"eb612b78-3e30-475d-99f9-6f704ccd1a71"},"_deposit":{"created_by":27,"id":"637","owners":[27],"pid":{"revision_id":0,"type":"depid","value":"637"},"status":"published"},"_oai":{"id":"oai:oist.repo.nii.ac.jp:00000637","sets":["6:51"]},"author_link":["2893"],"item_10001_biblio_info_7":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-08-14","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageStart":"e23051","bibliographicVolumeNumber":"55","bibliographic_titles":[{},{"bibliographic_title":"genesis","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"Author","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Gyoja, Fuki"}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Basic helix‐loop‐helix (bHLH) transcription factors have attracted the attention of developmental and evolutionary biologists for decades because of their conserved functions in mesodermal and neural tissue formation in both vertebrates and fruit flies. Their evolutionary history is of special interest because it will likely provide insights into developmental processes and refinement of metazoan‐specific traits. This review briefly considers advances in developmental biological studies on bHLHs/HLHs. I also discuss recent genome‐wide surveys and molecular phylogenetic analyses of these factors in a wide range of metazoans. I hypothesize that interactions between metazoan‐specific Group A, D, and E bHLH/HLH factors enabled a sophisticated transition system from cell proliferation to differentiation in multicellular development. This control mechanism probably emerged initially to organize a multicellular animal body and was subsequently recruited to form evolutionarily novel tissues, which differentiated during a later ontogenetic phase.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"John Wiley and Sons"}]},"item_10001_relation_13":{"attribute_name":"PubMedNo.","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:pmid/28804953","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1002/dvg.23051","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"Related site","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://onlinelibrary.wiley.com/doi/full/10.1002/dvg.23051","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2017 Wiley Periodicals, Inc."},{"subitem_rights":"This is the peer reviewed version of the following article: Gyoja F. Basic helix‐loop‐helix transcription factors in evolution: Roles in development of mesoderm and neural tissues. genesis. 2017;55:e23051., which has been published in final form at https://doi.org/10.1002/dvg.23051. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1526-968X","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"Author's flag","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-15"}],"displaytype":"detail","filename":"Gyoja bHLH Review v8.pdf","filesize":[{"value":"440.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Gyoja bHLH Review v8","url":"https://oist.repo.nii.ac.jp/record/637/files/Gyoja bHLH Review v8.pdf"},"version_id":"8bf9d04d-083c-47fc-a207-7fead9c0097c"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Basic helix-loop-helix transcription factors in evolution: Roles in development of mesoderm and neural tissues","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Basic helix-loop-helix transcription factors in evolution: Roles in development of mesoderm and neural tissues","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"27","path":["51"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-08-15"},"publish_date":"2018-08-15","publish_status":"0","recid":"637","relation_version_is_last":true,"title":["Basic helix-loop-helix transcription factors in evolution: Roles in development of mesoderm and neural tissues"],"weko_creator_id":"27","weko_shared_id":27},"updated":"2023-06-26T12:06:04.092881+00:00"}