{"created":"2023-06-26T11:00:23.782216+00:00","id":875,"links":{},"metadata":{"_buckets":{"deposit":"71b835a2-8fe2-4627-bdab-1ceeb3a1f609"},"_deposit":{"created_by":28,"id":"875","owners":[28],"pid":{"revision_id":0,"type":"depid","value":"875"},"status":"published"},"_oai":{"id":"oai:oist.repo.nii.ac.jp:00000875","sets":["6:67"]},"author_link":["4534","4524","4532","4527","4529","4535","4528","4531","4525","4536","4526","4530","4533"],"item_10001_biblio_info_7":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-08-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageStart":"1559325818790152","bibliographicVolumeNumber":"16","bibliographic_titles":[{},{"bibliographic_title":"Dose-Response","bibliographic_titleLang":"en"}]}]},"item_10001_creator_3":{"attribute_name":"Author","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Wang, Bing"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanaka, Kaoru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ninomiya, Yasuharu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maruyama, Kouichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Varès, Guillaume"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Katsube, Takanori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Murakami, Masahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Liu, Cuihua"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujimori, Akira"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujita, Kazuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Liu, Qiang"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Eguchi-Kasai, Kiyomi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nenoi, Mitsuru"}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"The existence of radiation-induced adaptive response (AR) was reported in varied biosystems. In mice, the first in vivo AR model was established using X-rays as both the priming and the challenge doses and rescue of bone marrow death as the end point. The underlying mechanism was due to the priming radiation-induced resistance in the blood-forming tissues. In a series of investigations, we further demonstrated the existence of AR using different types of ionizing radiation (IR) including low linear energy transfer (LET) X-rays and high LET heavy ion. In this article, we validated hematopoietic stem cells/hematopoietic progenitor cells (HSCs/HPCs) measured as endogenous colony-forming units-spleen (CFU-S) under AR inducible and uninducible conditions using combination of different types of IR. We confirmed the consistency of increased CFU-S number change with the AR inducible condition. These findings suggest that AR in mice induced by different types of IR would share at least in part a common underlying mechanism, the priming IR-induced resistance in the blood-forming tissues, which would lead to a protective effect on the HSCs/HPCs and play an important role in rescuing the animals from bone marrow death. These findings provide a new insight into the mechanistic study on AR in vivo.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"SAGE Publications "}]},"item_10001_relation_13":{"attribute_name":"PubMedNo.","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:pmid/30150909","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1177/1559325818790152","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://creativecommons.org/licenses/by-nc/4.0/"}]}]},"item_10001_relation_17":{"attribute_name":"Related site","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://journals.sagepub.com/doi/10.1177/1559325818790152","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2018 The Author(s).​"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1559-3258","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"Author's flag","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-05-16"}],"displaytype":"detail","filename":"Wang-2018-Increased Hematopoietic Stem Cells_H.pdf","filesize":[{"value":"380.4 kB"}],"format":"application/pdf","license_note":"Creative Commons\nAttribution 4.0 International\n(http://www.creativecommons.org/licenses/by-nc/4.0/)","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Wang-2018-Increased Hematopoietic Stem Cells_H","url":"https://oist.repo.nii.ac.jp/record/875/files/Wang-2018-Increased Hematopoietic Stem Cells_H.pdf"},"version_id":"902f3f4b-8180-4e3c-8d50-781d5cb234f6"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Increased Hematopoietic Stem Cells/Hematopoietic Progenitor Cells Measured as Endogenous Spleen Colonies in Radiation-Induced Adaptive Response in Mice (Yonezawa Effect)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Increased Hematopoietic Stem Cells/Hematopoietic Progenitor Cells Measured as Endogenous Spleen Colonies in Radiation-Induced Adaptive Response in Mice (Yonezawa Effect)","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"28","path":["67"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-05-16"},"publish_date":"2019-05-16","publish_status":"0","recid":"875","relation_version_is_last":true,"title":["Increased Hematopoietic Stem Cells/Hematopoietic Progenitor Cells Measured as Endogenous Spleen Colonies in Radiation-Induced Adaptive Response in Mice (Yonezawa Effect)"],"weko_creator_id":"28","weko_shared_id":28},"updated":"2023-06-26T12:01:02.064758+00:00"}