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Noninvasive technique to evaluate the muscle fiber characteristics using q-space imaging
https://oist.repo.nii.ac.jp/records/1015
https://oist.repo.nii.ac.jp/records/101503f13a64-dbdc-412c-9d9c-f2debccf82cf
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Hata-2019-Noninvasive technique to evaluate th (1.9 MB)
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Creative Commons
Attribution 4.0 International (https://creativecommons.org/licenses/by/4.0/) |
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-07-17 | |||||
| タイトル | ||||||
| タイトル | Noninvasive technique to evaluate the muscle fiber characteristics using q-space imaging | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者（英） |
Hata, Junichi
× Hata, Junichi× Nakashima, Daisuke× Tsuji, Osahiko× Fujiyoshi, Kanehiro× Yasutake, Kaori× Sera, Yasushi× Komaki, Yuji× Hikishima, Keigo× Nagura, Takeo× Matsumoto, Morio× Okano, Hideyuki× Nakamura, Masaya |
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| 書誌情報 |
en : PLOS ONE 巻 14, 号 4, p. e0214805, 発行日 2019-04-04 |
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| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Background Skeletal muscles include fast and slow muscle fibers. The tibialis anterior muscle (TA) is mainly composed of fast muscle fibers, whereas the soleus muscle (SOL) is mainly composed of slow muscle fibers. However, a noninvasive approach for appropriately investigating the characteristics of muscles is not available. Monitoring of skeletal muscle characteristics can help in the evaluation of the effects of strength training and diseases on skeletal muscles. Purpose The present study aimed to determine whether q-space imaging can distinguish between TA and SOL in in vivo mice. Methods In vivo magnetic resonance imaging of the right calves of mice (n = 8) was performed using a 7-Tesla magnetic resonance imaging system with a cryogenic probe. TA and SOL were assessed. q-space imaging was performed with a field of view of 10 mm x 10 mm, matrix of 48 x 48, and section thickness of 1000 mu m. There were ten b-values ranging from 0 to 4244 s/mm(2), and each b-value had diffusion encoding in three directions. Magnetic resonance imaging findings were compared with immunohistological findings. Results Full width at half maximum and Kurtosis maps of q-space imaging showed signal intensities consistent with immunohistological findings for both fast (myosin heavy chain II) and slow (myosin heavy chain I) muscle fibers. With regard to quantification, both full width at half maximum and Kurtosis could represent the immunohistological findings that the cell diameter of TA was larger than that of SOL (P < 0.01). Conclusion q-space imaging could clearly differentiate TA from SOL using differences in cell diameters. This technique is a promising method to noninvasively estimate the fiber type ratio in skeletal muscles, and it can be further developed as an indicator of muscle characteristics. |
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| 出版者 | ||||||
| 出版者 | Public Library of Science | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1932-6203 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | info:pmid/30947237 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.1371/journal.pone.0214805 | |||||
| 権利 | ||||||
| 権利情報 | © 2019 Hata et al. | |||||
| 情報源 | ||||||
| 関連名称 | https://creativecommons.org/licenses/by/4.0/ | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214805 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
