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Sex‐specific expression and DNA methylation in a species with extreme sexual dimorphism and paternal genome elimination
https://oist.repo.nii.ac.jp/records/2018
https://oist.repo.nii.ac.jp/records/2018e9be75bc-2f05-4648-9dac-5fde2cd460c2
名前 / ファイル | ライセンス | アクション |
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Bain-Sex-specific expression and DNA methylati (3.1 MB)
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Creative Commons Attribution 4.0 International(https://creativecommons.org/licenses/by/4.0/)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-04-27 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Sex‐specific expression and DNA methylation in a species with extreme sexual dimorphism and paternal genome elimination | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | doublesex | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | epigenetics | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | genomic imprinting | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | insects | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | mealybug | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Planococcus citri | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者(英) |
Bain, Stevie A.
× Bain, Stevie A.× Marshall, Hollie× Filia, Andrés G.× Laetsch, Dominik R.× Husnik, Filip× Ross, Laura |
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書誌情報 |
en : Molecular Ecology 発行日 2021-03-12 |
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抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Phenotypic differences between sexes are often mediated by differential expression and alternative splicing of genes. However, the mechanisms that regulate these expression and splicing patterns remain poorly understood. The mealybug, Planococcus citri, displays extreme sexual dimorphism and exhibits an unusual instance of sex-specific genomic imprinting, paternal genome elimination (PGE), in which the paternal chromosomes in males are highly condensed and eliminated from the sperm. Planococcus citri has no sex chromosomes and both sexual dimorphism and PGE are predicted to be under epigenetic control. We recently showed that P. citri females display a highly unusual DNA methylation profile for an insect species, with the presence of promoter methylation associated with lower levels of gene expression. Here, we therefore decided to explore genome-wide differences in DNA methylation between male and female P. citri using whole-genome bisulphite sequencing. We identified extreme differences in genome-wide levels and patterns between the sexes. Males display overall higher levels of DNA methylation which manifest as more uniform low levels across the genome. Whereas females display more targeted high levels of methylation. We suggest these unique sex-specific differences are due to chromosomal differences caused by PGE and may be linked to possible ploidy compensation. Using RNA-Seq, we identify extensive sex-specific gene expression and alternative splicing, but we find no correlation with cis-acting DNA methylation. | |||||
出版者 | ||||||
出版者 | John Wiley & Sons Ltd. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0962-1083 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1365-294X | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | info:pmid/33629415 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1111/mec.15842 | |||||
権利 | ||||||
権利情報 | © 2021 The Author(s). | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://onlinelibrary.wiley.com/doi/10.1111/mec.15842 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |