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  1. 学術雑誌論文
  2. 石川ユニット

Transcriptional Regulation of Differentiation and Functions of Effector T Regulatory Cells

https://oist.repo.nii.ac.jp/records/1119
https://oist.repo.nii.ac.jp/records/1119
3c8e1841-4178-4ca3-8a13-93d28bbf5696
名前 / ファイル ライセンス アクション
Koizumi-2019-Transcriptional Koizumi-2019-Transcriptional Regulation of Dif (759.5 kB)
Creative Commons Attribution 4.0 International (https://creativecommons.org/licenses/by/4.0/)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-10-23
タイトル
言語 en
タイトル Transcriptional Regulation of Differentiation and Functions of Effector T Regulatory Cells
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者(英) Koizumi, Shin-ichi

× Koizumi, Shin-ichi

WEKO 6228

Koizumi, Shin-ichi

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Ishikawa, Hiroki

× Ishikawa, Hiroki

WEKO 6229

Ishikawa, Hiroki

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書誌情報 en : Cells

巻 8, 号 8, p. 939, 発行日 2019-08-20
抄録
内容記述タイプ Other
内容記述 Foxp3-expressing regulatory T (Treg) cells can suppress the activity of various types of immune cells and play key roles in the maintenance of self-tolerance and in the regulation of immune responses against pathogens and tumor cells. Treg cells consist of heterogeneous subsets that have distinct phenotypes and functions. Upon antigen stimulation, naive-like thymus-derived Treg cells, which circulate in secondary lymphoid organs, can differentiate into effector Treg (eTreg) cells and migrate to and control immune homeostasis of peripheral tissues. eTreg cells are heterogeneous in terms of their ability to localize to specific tissues and suppress particular types of immune responses. Differentiation and function of diverse eTreg subsets are regulated by a variety of transcription factors that are activated by antigens and cytokines. In this article, we review the current understanding of the transcriptional regulation of differentiation and function of eTreg cells.
出版者
出版者 MDPI
ISSN
収録物識別子タイプ ISSN
収録物識別子 2073-4409
PubMed番号
関連タイプ isIdenticalTo
識別子タイプ PMID
関連識別子 info:pmid/31434282
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 info:doi/10.3390/cells8080939
権利
権利情報 © 2019 The Author(s).
情報源
関連名称 https://creativecommons.org/licenses/by/4.0/
関連サイト
識別子タイプ URI
関連識別子 https://www.mdpi.com/2073-4409/8/8/939
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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