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  1. 学術雑誌論文
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ZP4 Is Present in Murine Zona Pellucida and Is Not Responsible for the Specific Gamete Interaction

https://oist.repo.nii.ac.jp/records/1969
https://oist.repo.nii.ac.jp/records/1969
c8567de9-6a8b-47f3-a11c-f8b9a7343eba
名前 / ファイル ライセンス アクション
Izquierdo-Rico-2021-ZP4 Izquierdo-Rico-2021-ZP4 Is Present in Murine Z (3.7 MB)
Creative Commons Attribution 4.0 International(https://creativecommons.org/licenses/by/4.0/)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2021-03-09
タイトル
タイトル ZP4 Is Present in Murine Zona Pellucida and Is Not Responsible for the Specific Gamete Interaction
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 zona pellucida
キーワード
言語 en
主題Scheme Other
主題 ZP4
キーワード
言語 en
主題Scheme Other
主題 Mus musculus
キーワード
言語 en
主題Scheme Other
主題 murine phylogeny
キーワード
言語 en
主題Scheme Other
主題 oocyte
キーワード
言語 en
主題Scheme Other
主題 pseudogene
キーワード
言語 en
主題Scheme Other
主題 sperm
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者(英) Izquierdo-Rico, Mª José

× Izquierdo-Rico, Mª José

Izquierdo-Rico, Mª José

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Moros-Nicolás, Carla

× Moros-Nicolás, Carla

Moros-Nicolás, Carla

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Pérez-Crespo, Míriam

× Pérez-Crespo, Míriam

Pérez-Crespo, Míriam

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Laguna-Barraza, Ricardo

× Laguna-Barraza, Ricardo

Laguna-Barraza, Ricardo

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Gutiérrez-Adán, Alfonso

× Gutiérrez-Adán, Alfonso

Gutiérrez-Adán, Alfonso

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Veyrunes, Frédéric

× Veyrunes, Frédéric

Veyrunes, Frédéric

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Ballesta, José

× Ballesta, José

Ballesta, José

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Laudet, Vincent

× Laudet, Vincent

Laudet, Vincent

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Chevret, Pascale

× Chevret, Pascale

Chevret, Pascale

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Avilés, Manuel

× Avilés, Manuel

Avilés, Manuel

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書誌情報 en : Frontiers in Cell and Developmental Biology

巻 8, p. 626679, 発行日 2021-01-18
抄録
内容記述タイプ Other
内容記述 Mammalian eggs are surrounded by an extracellular matrix called the zona pellucida (ZP). This envelope participates in processes such as acrosome reaction induction, sperm binding, protection of the oviductal embryo, and may be involved in speciation. In eutherian mammals, this coat is formed of three or four glycoproteins (ZP1-ZP4). While Mus musculus has been used as a model to study the ZP for more than 35 years, surprisingly, it is the only eutherian species in which the ZP is formed of three glycoproteins Zp1, Zp2, and Zp3, Zp4 being a pseudogene. Zp4 was lost in the Mus lineage after it diverged from Rattus, although it is not known when precisely this loss occurred. In this work, the status of Zp4 in several murine rodents was tested by phylogenetic, molecular, and proteomic analyses. Additionally, assays of cross in vitro fertilization between three and four ZP rodents were performed to test the effect of the presence of Zp4 in murine ZP and its possible involvement in reproductive isolation. Our results showed that Zp4 pseudogenization is restricted to the subgenus Mus, which diverged around 6 MYA. Heterologous in vitro fertilization assays demonstrate that a ZP formed of four glycoproteins is not a barrier for the spermatozoa of species with a ZP formed of three glycoproteins. This study identifies the existence of several mouse species with four ZPs that can be considered suitable for use as an experimental animal model to understand the structural and functional roles of the four ZP proteins in other species, including human.
出版者
出版者 Frontiers Media
ISSN
収録物識別子タイプ ISSN
収録物識別子 2296-634X
PubMed番号
関連タイプ isIdenticalTo
識別子タイプ PMID
関連識別子 info:pmid/33537315
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 info:doi/10.3389/fcell.2020.626679
権利
権利情報 © 2021 Izquierdo-Rico, Moros-Nicolás, Pérez-Crespo, Laguna-Barraza, Gutiérrez-Adán, Veyrunes, Ballesta, Laudet, Chevret and Avilés.
関連サイト
識別子タイプ URI
関連識別子 https://www.frontiersin.org/articles/10.3389/fcell.2020.626679/full
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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